The Only Bit of “Good News” From 2015

WINDSOR, ON / ACCESSWIRE / December 14, 2015 / The Wealthy Biotech Trader (or“WBT”), an investment newsletter focused on showing everyday investors new opportunities in rapidly growing, little-known biotech, pharma, medical device and general healthcare stocks making news and subsequent market moves, would like to mention a few highlights from 2014/ 2015 in the crazy world of biotech investing.

In 2014 51 new medicines were approved by the FDA, the most in almost 20 years. A whopping 8 of those approvals were new drugs for cancer treatment–since 1990, cancer death rates have declined nearly 22%–and approximately 83% of the survival gains are attributable to new treatments.

And although 2015 is shaping up to be another banner year for scientific and drug breakthroughs for cancer, there are a few areas in oncology (cancer treatment) that most pharma companies are having a very difficult time seeing any meaningful progress.

Pancreatic cancer is by most measures the deadliest of the 200+ cancers as evidenced by its 7% 5-year survival rate–meaning only 7% of people diagnosed with this horrific killer will live longer than 5 years. 75% of patients die in the first year, and only a few out of 100 will live longer that 10 years. In nearly 40 years there has been virtually no improvement in the overall survival rates in those diagnosed with pancreatic cancer. Until now?

One tiny Australian biotech company is working on a novel compound / drug that they have recently stated could have a major impact on this deadly disease. The company is pre-clinical, but has just released very compelling news of shrinking pancreatic cancer tumors in mice by 84% in only 26 days (click the next paragraph to read the news).

Propanc Heath Group (PPCH) News: Propanc Demonstrates Significant Anti-Tumor Efficacy in Pancreatic and Ovarian Cancer Preclinical Models; Files Patent Specifying New Therapeutic Target Dose Range

Investors will be watching PPCH like a hawk over the next 1-3 months as they wrap up their“animal studies” and prepare their “Initial New Drug” application with the FDA. The company has stated in news releases they have the cash in the bank to get to that point, which could be a huge inflection point for shareholder value creation if approved by the FDA.

338,000 new cases of pancreatic cancer are diagnosed each year, which is why SeeThruEquity, a research firm, has pegged a global market for treating this cancer at roughly $9 billion. If PPCHshows any results in results on humans in clinical testing they will no doubt be an attractive target acquisition by a larger pharma company which could be at a much higher price per share than the current market prices ($0.04).

Another company working on a treatment for pancreatic cancer is Immunomedics Inc. (IMMU). Immunomedics’ most advanced candidate is 90Y-clivatuzumab tetraxetan. The radiolabeled antibody is in a Phase 3 registration trial in patients with advanced pancreatic cancer. Immunomedics expects patient enrollment to be completed in calendar year 2016. This product candidate utilizes radioimmunotherapy, or RAIT, which combines the targeting power of monoclonal antibodies with the cell-damaging ability of localized radiation. WBT feels that there are better ways to deliver and apply certain existing forms of treatment, and IMMU appears to have a novel approach using a more efficient, localized form of radiation combined with the very hot newer form of treatment, immunotherapy, or harnessing the bodies ability to fight cancer.

Aduro Biotech Inc.’s (ADRO) new GVAX drug appears to be promising for the potential treatment of late-stage pancreatic cancer but could still be some distance from actual approval. Like Immunomedics, ADRO is an immunotherapy company–harnessing the body’s own ability to fight cancer–but Aduro’s LADD technology platform is based on proprietary attenuated (genetically modified to be harmless to the patient) strains of Listeria that have been engineered to express tumor-associated antigens to induce specific and targeted immune responses. In other words, ADRO’s drug candidate is a harmless form of listeria introduced into the body in order to provoke a “immuno-response” from the patient which in turn helps fight tumor cells. ADRO is in phase 2 in trials of GVAX and any news could send the stock soaring or cratering–Investors just need to place their bets!

Another biotech playing in the pancreatic cancer space is an example of what can go wrong if you do not do your homework on your investments, or maybe just a plain and simple example of how bad luck can strike. Threshold Pharmaceuticals Inc. (THLD) had a sweetheart deal with the German drug giant Merck & Co. (NYSE:MRK) which had the pharma giant pay roughly $50 million in various fees and costs associated with THLD’s development of their lead product Evofosfamine only to see it be rejected in phase 3 by the FDA this week. The stock plummeted 80%+.

Its been 10 years since THLD’s chart peaked at about $100/ share (it hit a low of $0.60 this week) which corresponded with their positive phase 1 results of the same drug, Evofosfamine. The sheer time to get this product through trials combined with the constant decline in share price over the same time-frame should have been a clue to Investors that this may not be as ground-breaking as once thought. Once lesson for biotech investors would be to take profits on the initial hype which surrounds a company/ stock at the beginning of a human clinical trial.

One thing is sadly for certain: the $100 billion+ market for cancer treatments is set to grow at an astounding rate for the foreseeable future. The average Investor undoubtedly does not know of the recent strides small and large pharma companies have been making, but we at the WBT see much of the capital flows from energy and materials flowing into healthcare, and more specifically into biotech. For a primer on the wonderful things being developed in the world of oncology readers may want to also research some of the following new blockbuster drugs:

– Cyramza, a stomach cancer treatment from Eli Lilly (NYSE:LLY)

– Opdivo, approved for advanced melanoma from Bristol-Myers Squibb (NYSE:BMY)

– Keytruda, a first-in-class melanoma drug from Merck (NYSE:MRK)

– Blincyto, a treatment for a rare form of acute lymphoblastic leukemia from Amgen (NASDAQ:AMGN)

The Wealthy Biotech Trader is always researching new trade ideas which have the makings for large market moves. Traders are urged to follow our parent outlet, The Wealthy Venture Capitalist on social media (see below) to stay apprised. We are an anti-email media outlet, and as such will only be releasing our reports/ updates/ news through Text Message Alerts, Twitter and Facebook.


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This report/release/profile is a commercial advertisement and is for general information and entertainment purposes only. We are engaged in the business of marketing and advertising companies for monetary compensation unless otherwise stated below. The Wealthy Biotech Trader and its employees are not a Registered Investment Advisors, Broker Dealers or a member of any association for other research providers in any jurisdiction whatsoever and we are not qualified to give financial advice. The information contained herein is based on sources which we believe to be reliable but is not guaranteed by us as being accurate and does not purport to be a complete statement or summary of the available data. The Wealthy Biotech Trader encourages readers and investors to supplement the information in these reports with independent research and other professional advice. All information on featured companies is provided by the companies profiled through their website, news releases, and corporate filings, or is available from public sources and The Wealthy Biotech Trader makes no representations, warranties or guarantees as to the accuracy or completeness of the disclosure by the profiled companies. The Private Securities Litigation Reform Act of 1995 provides investors a ‘safe harbor’ in regard to forward-looking statements. Any statements that express or involve discussions with respect to predictions, expectations, beliefs, plans, projections, objectives, goals, assumptions or future events or performance are not statements of historical fact may be “forward looking statements.” Forward looking statements are based on expectations, estimates, and projections at the time the statements are made that involve a number of risks and uncertainties which could cause actual results or events to differ materially from those presently anticipated. Forward looking statements in this action may be identified through use of words such as “projects,” “foresee,” “expects,” “will,” “anticipates,” “estimates,” “believes,” “understands,” or that by statements indicating certain actions “may,” “could,” or “might” occur. Understand there is no guarantee past performance will be indicative of future results.

The Wealthy Biotech Trader’s parent company has been and will be compensated $10,000 per month by Propanc Heath Group. The Wealthy Biotech Trader’s controlling parent company has also been compensated $60,000 by Propanc Heath Group in the form of a convertible note and readers should understand that they will convert this note into common shares sell them into the market as soon as the statutory 144 hold period has lapsed. The Wealthy Biotech Trader’s controlling parent company has also been compensated 4 million restricted shares of Propanc by Propanc Health Group.

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SOURCE: The Wealthy Biotech Trader

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